For clinically significant scorpion envenomation, what is the first line therapy for sympathomimetic toxicity?

In cases of clinically significant scorpion envenomation associated with sympathomimetic toxicity, the first-line therapy is benzodiazepines. Benzodiazepines are effective in this scenario as they provide sedation and help to control the overstimulation of the central nervous system that can occur due to the release of catecholamines and excessive sympathetic activity caused by the venom.

Benzodiazepines can alleviate agitation, reduce muscle spasms, and decrease autonomic overactivity, which are common symptoms associated with scorpion envenomation. By managing these symptoms, benzodiazepines not only improve patient comfort but also help stabilize vital signs. This approach is crucial in symptomatic management, allowing other supportive treatments to be administered more effectively.

Other options do not address the specific symptoms associated with sympathomimetic toxicity as effectively as benzodiazepines do. For example, while antihistamines may help with allergic reactions, they do not provide sedative effects or control sympathetic overactivity. Opioids, although effective for pain management, do not directly address hyperactivity of the sympathetic nervous system and can lead to respiratory depression. Fluids and electrolytes may be essential for overall support in a critical situation but do not specifically target the central nervous system effects of