How long can whole blood collected in the anticoagulant CPDA-1 be stored?

Whole blood collected with the anticoagulant CPDA-1 can be stored for up to 35 days. This storage period is essential for maintaining the viability of the blood components, allowing them to remain functional and safe for transfusion. CPDA-1, which stands for Citrate-Phosphate-Dextrose-Adenine-1, works as an anticoagulant and preservative. The citrates in CPDA-1 prevent coagulation, while the phosphates help maintain the pH balance and the dextrose provides energy for the red blood cells during storage.

The shelf life of 35 days is critical for healthcare providers to ensure that the blood products are available for patients in need without compromising quality. Extended storage beyond this timeframe would negatively impact the red blood cell's functionality, leading to decreased oxygen-carrying capacity and increased likelihood of adverse reactions during transfusion. Understanding this timeframe helps medical personnel manage blood inventory effectively and ensures that patients receive safe and effective transfusions.