True or False: Low molecular weight heparin (LMWH) increases the risk of spinal or epidural hematoma during epidural anesthesia.

Low molecular weight heparin (LMWH) does indeed increase the risk of spinal or epidural hematoma during epidural anesthesia. This is due to the anticoagulant effects of LMWH, which can interfere with hemostasis and increase the likelihood of bleeding in the vicinity of the epidural space. When an epidural needle is inserted, there is a potential risk for bleeding, and the presence of LMWH heightens that risk, especially if the medication has been administered shortly before the procedure.

Epidural hematoma can lead to serious complications, including paralysis, and awareness of the timing of LMWH administration relative to the procedure is crucial for healthcare providers. Therefore, holding LMWH prior to epidural anesthesia is often recommended in clinical practice to mitigate this risk.

While the other response choices might suggest there could be varying levels of risk or conditions under which LMWH might not pose a risk, the evidence supports a clear association between LMWH and an increased risk of spinal or epidural hematoma during such procedures. Thus, the statement is accurately true.