What is a significant symptom of phosgene exposure at high concentrations?

Severe cough with laryngospasm is a significant symptom of phosgene exposure at high concentrations due to the compound's impact on the respiratory system. Phosgene is a toxic gas that, when inhaled, can cause serious injury to the lungs and airways. The irritation of the respiratory tract leads to acute symptoms, particularly at higher levels of exposure.

Laryngospasm, which is a sudden spasm of the vocal cords that can hinder breathing, is a critical response to the irritation caused by phosgene inhalation. This severe coughing and laryngospasm indicate that the airway is compromised, which is a medical emergency and suggests that the individual may be at risk of respiratory failure. The combination of these symptoms underscores the gravity of phosgene exposure and the need for immediate medical intervention.

Other symptoms associated with phosgene exposure, such as headache and dizziness, nausea and vomiting, and sore throat and chest pain, may also occur but are not as immediately life-threatening or indicative of severe respiratory distress as a severe cough with laryngospasm. Recognizing the severe cough with laryngospasm as a key symptom can help in prioritizing appropriate emergency response and treatment.