What is the target blood glucose level to avoid complications in TBI patients?

The target blood glucose level of 180 mg/dL is supported by research indicating that maintaining glucose levels within this range is crucial for preventing complications in patients with traumatic brain injury (TBI). Hyperglycemia, or elevated blood glucose levels, can exacerbate neurological damage and inflammatory responses, complicating recovery post-injury. Keeping blood glucose levels below 180 mg/dL has been associated with improved outcomes in TBI patients, including reduced risk of secondary brain injury.

Other proposed target ranges, such as 120 mg/dL or 150 mg/dL, may be too stringent, leading to the risk of hypoglycemia, which can also be detrimental to brain function. A target of 200 mg/dL may be too high, increasing the risk of hyperglycemia-related complications. Thus, the goal of 180 mg/dL represents a balanced approach to managing glucose levels while minimizing potential harm to the TBI patient.