Which statement is true regarding hypoglycemia and hyperglycemia in relation to brain health?

Hypoglycemia is indeed considered more harmful than hyperglycemia when it comes to brain health. The brain relies heavily on glucose as its primary source of energy, and when blood sugar levels drop excessively, as seen in hypoglycemia, it can lead to significant neurological impairments. The brain does not store glucose, so a lack of glucose can result in brain dysfunction that can manifest as confusion, seizures, loss of consciousness, or even permanent damage if not rapidly corrected.

While hyperglycemia, or elevated blood sugar levels, can also pose risks, particularly in the context of chronic diabetes management, its immediate effects on brain function are generally less severe than those caused by hypoglycemia. Hyperglycemia can lead to complications such as diabetic ketoacidosis or hyperglycemic hyperosmolar state, which may have long-term effects on brain health if untreated; however, the acute dangers presented by low blood sugar levels highlight hypoglycemia's more significant threat to immediate brain function and health.