Which substance is NOT a highly water soluble irritant?

Phosgene is a chemical compound that acts as a toxic irritant, but it is not considered a highly water-soluble irritant. Phosgene has low solubility in water, which means that it does not readily dissolve in water to a significant extent. Instead, it can exist in the air as a gas at room temperature, posing a risk primarily through inhalation rather than through contact with water.

In contrast, substances such as oxides of nitrogen, acids, and alcohols typically demonstrate high solubility in water. These substances can dissolve and ionize in aqueous solutions, increasing their potential to cause irritation upon exposure. Oxides of nitrogen, particularly nitrogen dioxide, can react with water in the lungs, while strong acids and alcohols also cause irritation through their interactions with moist tissues. Therefore, understanding the solubility characteristics of these compounds is crucial for assessing their potential health risks and managing exposure effectively.